PowerShell can invoke Microsoft Excel sheets and start contained macros. While this would work with an invisible Excel application window, it is a wise idea to keep Excel open (as shown below) to spot warning messages that might appear when you try and run security sensitive things like macros:
# file path to your XLA file with macros
$FilePath = "c:\test\file.xla"
# macro name to run
$Macro = "AddData"
$excel = New-Object -ComObject Excel.Application
$excel.Visible = $true
$wb = $excel.Workbooks.Add($FilePath)
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