Mail Server Configuration Settings Never Save

As the subject of this post, even something as simple as changing the default 'SMTP Sender' from say "uptime Monitoring Station" to just "uptime" causes a never ending spinning timer next to the Save / Saving button, the change never saves successfully.

This behaviour occurs even after a reboot of the server (Version: 7.7.2 (build 6), OS: Windows Server 2008 R2 (amd64) 6.1 Service Pack 1).

Thank you for any help anyone is able to provide.